The effect of electron beam on erythrocytes in pathology
Gogoleva T.E.1, Mamaeva S.N.1, Rychkov M.M.2, Maksimov G.V.3
1North-Eastern Federal University, Yakutsk, Russia
2Tomsk Polytechnic University, Tomsk, Russia
3Lomonosov Moscow State University, Moscow, Russia
Email: gogoltakuo98@mail.ru
Venous erythrocytes of patients diagnosed with breast cancer were examined using a scanning electron microscope (SEM). The samples are dry smears on slides previously irradiated with electron beam (50, 100, 150 Gy) on a CMB-8 betatron. SEM images were obtained, cell sizes and shapes were analyzed, the percentage of morphological types was determined, histograms of the size distribution were constructed, and nanoscale structures on the surface were detected. Significant morphological changes have been identified. Nanoscale structures persist after irradiation, which may indicate their viral nature. Keywords: erythrocytes, ionizing radiation, electron beam, betatron, intraoperative radiation therapy, breast cancer, nanoscale structures.
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